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  Deep Venous Thrombosis


Thrombosis refers to the formation of a blood clot. Deep venous thrombosis refers to clot formation (most commonly) in the lower extremities. The release of the clot, allowing it to travel through the blood stream, is known as embolization. This can result in clot entrapment in the lungs, a clinical entity known as pulmonary embolism.
 
Symptoms
Common symptoms include unilateral leg (calf) swelling and pain. There may be tenderness to the calf extending up the thigh, into the groin.
 
Risk Factors
Deep venous thrombosis (DVT) is common in several different situations:
 

Pregnancy
Chronically bedridden or wheelchair bound
Elderly patients
Immediate post operative patients
Females using birth control pills
Patients with a history of prior deep venous thrombosis
 
Diagnosis
Evaluation will include history and physical examination for the findings consistent with DVT.
 
Echography, especially Doppler, has offered a painless noninvasive alternative for diagnosing this problem.
Venography, which involves an injection of a radio opaque contrast dye into a foot vein, provides X-ray illumination of the lower extremity venous system.
Blood tests (i.e. blood count and coagulation profile) will also be performed.
 
Treatment
Treatment will involve the use of medications (heparin) to inhibit clot formation. This anticoagulant medication is generally given in the hospital by intravenous or subcutaneous route with close observation for signs and symptoms of pulmonary embolism. Leg elevation, bed rest, and warm compresses may also be indicated. Oral anticoagulant medication (warfarin) may be necessary longer term in some of these patients.

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